GHS REFERENCE / H-CODES / H412

H412 — Harmful to aquatic life with long lasting effects

The GHS hazard statement for hazardous to the aquatic environment — chronic, category 3. Here is what it means, the label elements that travel with it, and the substances that carry it.

At a glance

Official statementHarmful to aquatic life with long lasting effects.
Hazard classHazardous to the aquatic environment — chronic
CategoryCategory 3
Signal wordNo signal word
PictogramNone assigned

What it means

Harmful to aquatic life over longer exposures, factoring in whether the substance degrades or accumulates. Environmental classes appear on SDSs and labels, but in the US they sit with EPA and DOT rather than OSHA.

Precautionary statements paired with H412

When the engine writes SDS Section 2 or a container label for a product carrying H412, these are the P-codes it assigns, in the official Annex 3 groups:

PreventionP273Avoid release to the environment.
DisposalP501Dispose of contents/container in accordance with local/regional/national/international regulations.

Substances that carry H412

458 of the 4,225 substances in our database carry H412 when classified in pure form — recognizable examples:

  • d-limonene — CAS 5989-27-5
  • ammonia — CAS 1336-21-6
  • (1S-cis)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride — CAS 172015-79-1
  • (2-(1,3-dioxolan-2-yl)ethyl)triphenylphosphonium bromide — CAS 86608-70-0

Same hazard class: H410 · H411 · H413

Reference information, not legal or professional advice. Statement texts and allocations follow GHS Rev 9 / 29 CFR 1910.1200 Appendix C as implemented by our classification engine; the regulatory text and agency practice control. Claims last reviewed July 23, 2026.

The engine writes these for you.

When SDS HQ authors an SDS or a container label, it assigns the hazard statements, signal word, pictograms, and precautionary statements from these same tables — automatically, with the calculation shown.

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