GHS REFERENCE / H-CODES / H373

H373 — May cause damage to organs through prolonged or repeated exposure

The GHS hazard statement for specific target organ toxicity, repeated exposure, category 2. Here is what it means, the label elements that travel with it, and the substances that carry it.

At a glance

Official statementMay cause damage to organs through prolonged or repeated exposure.
Hazard classSpecific target organ toxicity, repeated exposure
CategoryCategory 2
Signal wordWarning
PictogramGHS08 Health hazardGHS08 — Health hazard

What it means

Damage to a specific organ or body system from prolonged or repeated exposure — the classic occupational-disease pattern (Category 1: known or presumed in humans; Category 2: suspected).

Precautionary statements paired with H373

When the engine writes SDS Section 2 or a container label for a product carrying H373, these are the P-codes it assigns, in the official Annex 3 groups:

PreventionP260Do not breathe dust/fume/gas/mist/vapors/spray.
ResponseP314Get medical advice/attention if you feel unwell.
DisposalP501Dispose of contents/container in accordance with local/regional/national/international regulations.

Substances that carry H373

347 of the 4,225 substances in our database carry H373 when classified in pure form — recognizable examples:

  • toluene — CAS 108-88-3
  • phenol — CAS 108-95-2
  • ((4-phenylbutyl)hydroxyphosphoryl)acetic acid — CAS 83623-61-4
  • (1RS,2SR,5RS — CAS 125225-28-7

Same hazard class: H372

Reference information, not legal or professional advice. Statement texts and allocations follow GHS Rev 9 / 29 CFR 1910.1200 Appendix C as implemented by our classification engine; the regulatory text and agency practice control. Claims last reviewed July 23, 2026.

The engine writes these for you.

When SDS HQ authors an SDS or a container label, it assigns the hazard statements, signal word, pictograms, and precautionary statements from these same tables — automatically, with the calculation shown.

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