H373 — May cause damage to organs through prolonged or repeated exposure

The GHS hazard statement for specific target organ toxicity, repeated exposure, category 2. Here is what it means, the label elements that travel with it, and the substances that carry it.

AT A GLANCE · OFFICIAL STATEMENT
“May cause damage to organs through prolonged or repeated exposure.”
HAZARD CLASS
Specific target organ toxicity, repeated exposure
CATEGORY
Category 2
SIGNAL WORD
Warning

What it means

Damage to a specific organ or body system from prolonged or repeated exposure — the classic occupational-disease pattern (Category 1: known or presumed in humans; Category 2: suspected).

Precautionary statements paired with H373

When the engine writes SDS Section 2 for a product carrying H373, these are the precautionary statements it assigns, with combined statements written as one line:

Substances that carry H373

349 of the 4,228 substances in our database carry H373 when classified in pure form — recognizable examples:

toluene
CAS 108-88-3
phenol
CAS 108-95-2
ethanediol
CAS 107-21-1
((4-phenylbutyl)hydroxyphosphoryl)acetic acid
CAS 83623-61-4
SAME HAZARD CLASS:H372

Reference information, not legal or professional advice. Statement texts and allocations follow 29 CFR 1910.1200 Appendix C (the GHS as adopted by OSHA HazCom 2024) as implemented by our classification engine; the regulatory text and agency practice control. Claims last reviewed July 23, 2026.

The engine writes these for you.

When SDS HQ authors an SDS, it assigns the hazard statements, signal word, pictograms, and precautionary statements from these same tables — automatically, with the calculation shown.