H310 — Fatal in contact with skin
The GHS hazard statement for acute toxicity, dermal, categories 1 and 2. Here is what it means, the label elements that travel with it, and the substances that carry it.
At a glance
| Official statement | Fatal in contact with skin. |
| Hazard class | Acute toxicity, dermal |
| Category | Categories 1 and 2 |
| Signal word | Danger |
| Pictogram |  GHS06 — Skull and crossbones |
What it means
Serious harm from skin contact over a single short exposure. Categories are set from acute toxicity estimates (ATE) per GHS Chapter 3.1.
Precautionary statements paired with H310
When the engine writes SDS Section 2 or a container label for a product carrying H310, these are the P-codes it assigns, in the official Annex 3 groups:
| Prevention | P262 | Do not get in eyes, on skin, or on clothing. |
| P264 | Wash hands and exposed skin thoroughly after handling. | |
| P280 | Wear protective gloves/protective clothing/eye protection/face protection. | |
| Response | P302 | IF ON SKIN: |
| P310 | Immediately call a POISON CENTER or doctor. | |
| P321 | Specific treatment (see supplemental first-aid instructions on this label). | |
| P361 | Take off immediately all contaminated clothing. | |
| P363 | Wash contaminated clothing before reuse. | |
| Storage | P405 | Store locked up. |
| Disposal | P501 | Dispose of contents/container in accordance with local/regional/national/international regulations. |
Substances that carry H310
3 of the 4,225 substances in our database carry H310 when classified in pure form — recognizable examples:
- 2-Mercaptoethanol (BME) — CAS 60-24-2
- acetone oxime — CAS 127-06-0
- peracetic acid . . . % — CAS 79-21-0
The engine writes these for you.
When SDS HQ authors an SDS or a container label, it assigns the hazard statements, signal word, pictograms, and precautionary statements from these same tables — automatically, with the calculation shown.